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足月非胎膜早破妊娠中组织学绒毛膜羊膜炎的影响因素

Factors Influencing Histologic Chorioamnionitis in Full-term Nonpremature Rupture of Membranes Pregnancy
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摘要 目的初步探究足月非胎膜早破妊娠中组织学绒毛膜羊膜炎(histologic chorioamnionitis,HCA)的影响因素。方法选取2018年1月—2020年9月于遵义医科大学附属医院产科分娩的843名产妇为研究对象,按胎膜病理分为HCA组(549例)和非HCA组(294名)。针对足月非胎膜早破妊娠中组织学绒毛膜羊膜炎的各因素进行单因素及多因素Logistic回归分析。结果两组在孕周、产次、分娩方式、羊水胎粪污染(MSAF)、前置胎盘、瘢痕子宫、先兆子宫破裂、高龄方面比较,差异有统计学意义(P<0.05)。多因素Logistic回归分析发现,MSAF是HCA发生的独立危险因素(OR=1.684,95%CI:1.186~2.391,P<0.05)。结论足月非胎膜早破妊娠中MSAF是HCA发生的危险因素,为改善新生儿结局,对伴有MSAF分娩产妇应关注胎盘病理学改变。 Objective To preliminarily investigate the factors influencing histologic chorioamnionitis(HCA)in fullterm non-premature rupture of membranes pregnancy.Methods A total of 843 women who delivered in department of obstetrics in the Hospital of Zunyi Medical University from January 2018 to September 2020 were selected as the study objects,and according to the fetal membrane pathology,they were divided into the HCA group(549 cases)and the non-HCA group(294 people).Conducted univariate and multivariate Logistic regression analysis on various factors of histological chorioamnionitis in term non premature rupture of membranes pregnancy.Results There were statistically significant difference in pregnant age,delivery time,delivery mode,meconium-stained amniotic fluid(MSAF),placenta previa,scar uterus,threatened uterine rupture,advanced age between the two groups(P<0.05).Multivariate Logistic regression analysis identified MSAF as a single risk factor for HCA(OR=1.684,95%CI:1.186-2.391,P<0.05).Conclusion MSAF is a risk factor for HCA in full-term non-premature rupture of membranes pregnancy,and to improve neonatal outcome,attention should be paid to placental pathological changes in deliveries women with MSAF.
作者 浦仕贤 彭坤航 尚钦 胡琼 PU Shixian;PENG Kunhang;SHANG Qin;HU Qiong(Department of Obstetrics,Affiliated Hospital of Zunyi Medical University,Zunyi,Guizhou Province,655630 China)
出处 《系统医学》 2023年第2期152-156,共5页 Systems Medicine
关键词 绒毛膜羊膜炎 组织学绒毛膜羊膜炎 羊水胎粪污染 胎儿炎症综合反应 Chorioamnionitis Histologic chorioamnionitis Meconium-stained amniotic fluid Fetal inflammatory syndrome
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