吉兰-巴雷综合征的神经心理症状及治疗进展

Neuropsychological symptoms and treatment of Guillain-Barrésyndrome:recent progress

急性炎性疾病伴随的神经心理症状逐渐引起临床医师的重视。吉兰-巴雷综合征(GBS)是一种获得性炎性多发神经根神经病,影响运动、感觉及自主神经系统,为引起急性瘫痪最常见的神经系统疾病之一。随着对该病认识的深入,GBS的神经心理症状逐渐引起关注,然而目前报道尚少,没有统一的诊断标准,也缺乏对治疗的研究。此外,神经心理症状对GBS患者康复及社会功能的影响不容忽视。本文归纳了GBS患者疲劳、焦虑、抑郁、认知障碍和睡眠障碍等神经心理症状的特点和诊治进展,以提高神经专科医师对GBS患者神经心理症状的认识,加强对GBS神经心理症状的评估与干预。

Neuropsychological symptoms of acute inflammatory diseases have gradually attracted the attention of clinicians.Guillain-Barrésyndrome(GBS)is a post-infectious autoimmune polyneuropathy which affects motor,sensory,and autonomic nerves.It is one of the most common neurological disorders resulting in acute paralysis.With the in-depth understanding of the disease,the neuropsychological symptoms of GBS have gradually attracted attention.However,researches on the neuropsychological symptoms of GBS are still scarce and there are still no diagnostic criteria and only few studies focusing on the treatment.In addition,the influence of neuropsychological symptoms on the rehabilitation and social function of GBS patients could not be ignored.This article summarized the characteristics,diagnosis and treatment progress of GBS patients with neuropsychological symptoms such as fatigue,anxiety,depression,cognitive disorders,and sleep disorders.Neurologists should improve the understanding of the neuropsychological symptoms of GBS patients and attach importance to the evaluation and intervention of neuropsychological symptoms of GBS.