营养支持治疗对恶性肿瘤患者免疫功能影响的研究进展

Research progress on effect of nutritional support therapy on immune function of patients with malignant tumor

恶性肿瘤是世界上病死率最高的疾病之一。在过去的几十年里,尽管在降低恶性肿瘤发病率和病死率方面取得了相当大的进展,但是每年仍有1000万例肿瘤患者死亡。恶性肿瘤患者常面临着营养不良的风险,而营养不良发生率高、治疗率低是我国现状。目前大量的研究已经证实,营养支持治疗可以纠正恶性肿瘤患者的营养不良、改善免疫功能、降低感染性疾病发生率,提高患者对治疗的耐受性,延长患者生存期。现就营养支持治疗对恶性肿瘤患者免疫功能的影响进行综述。

Malignant tumor is one of the most deadly diseases in the world.Over the past few decades,10 million tumor patients have died each year,despite considerable progress in reducing the incidence and mortality of malignant tumors.The patients with malignant tumors are at risk of malnutrition.The high incidence of malnutrition and low treatment rate is the current situation in our country.A large number of studies have confirmed that the nutritional support therpy can correct malnutrition,improve immune function,reduce the occurrence of infectious diseases,increase the tolerance to treatment and prolong the survival period in the patients with malignant tumors.This article reviews the effect of nutritional support therapy on the immune function of the patients with malignant tumor.