乳腺癌的个性化早期发现和预防

Personalized Early Detection and Prevention of Breast Cancer

对于乳腺癌个性化早期检测和预防而言,致力于实现循证的个性化干预,能有效增加现有乳腺癌筛检和预防方案的优点并减少其危害,本文综述以下几个重点:(1)适用于所有妇女的乳腺癌亚型特异性风险评估工具;(2)对预防措施反应的中间标志物;(3)减少预后不良的乳腺癌发病率的新型非手术预防措施。在本综述中,探讨了乳腺癌风险预测、风险分层预防的现状。

For personalized early detection and prevention of breast cancer,are committed to implementing evidencebased personalized intervention,which can effectively increase the advantages of existing breast cancer screening and prevention programs and reduce their harm.This paper summarizes the following key points:1.breast cancer subtype specific risk assessment tool for all women;2.Intermediate markers in response to preventive measures;3.New non operative preventive measures to reduce the incidence rate of breast cancer with poor prognosis.In this review,the status quo of risk prediction and risk stratification prevention of breast cancer was discussed.