认知行为团体疗法联合抗抑郁药物对强迫症患者的临床疗效

Clinical Efficacy of Cognitive-behavioral Group Therapy Combined with Antidepressants on Patients with Obsessive-compulsive Disorder

目的探讨认知行为团体疗法联合抗抑郁药物对强迫症患者的治疗效果。方法随机选取2020年1月—2021年2月黑龙江省第三医院收治的70例强迫症患者为研究对象,随机分为对照组和认行团疗组,各35例。对照组患者采用抗抑郁药物(阿立哌唑+舍曲林)治疗,认行团疗组联合认知行为团体疗法。对比两组强迫症状及信念改善情况,对比两组疗效,检测情绪异常及生活质量变化。结果认行团疗组治疗后Y-BOCS(12.45±4.13)分、OBQ-44评分(101.32±28.69)分均显著低于对照组,差异有统计学意义(t=5.238,P=0.011)。认行团疗组强迫症治疗总有效率(97.14%)显著高于对照组(74.29%),差异有统计学意义(χ^(2)=7.467,P=0.006)。认行团疗组治疗后HAMD(22.65±4.85)分和HAMA(18.78±4.37)分显著低于对照组,差异有统计学意义(t=6.792、8.408,P<0.05)。结论抗抑郁药物治疗强迫症基础上,实施认知行为团体疗法,对患者强迫信念、负性情绪纠正效果显著,可有效提升疗效,改善其日常症状,提升预后生活质量,该方案治疗价值较高。

Objective To explore the therapeutic effect of cognitive behavioral group therapy combined with antidepressant drugs on patients with obsessive-compulsive disorder.Methods 70 patients with obsessive-compulsive disorder admitted to the Third Hospital of Heilongjiang Province from January 2020 to February 2021 were randomly selected as the research subjects,and randomly divided into a control group and a group therapy group,with 35 patients in each group.The control group patients were treated with antidepressant drugs(aripiprazole+sertraline),while the group therapy group combined with cognitive behavioral group therapy.Compare the improvement of obsessivecompulsive symptoms and beliefs between two groups,compare the efficacy of the two groups,and detect emotional abnormalities and changes in quality of life.Results After treatment,the Y-BOCS(12.45±4.13)points and OBQ-44 score(101.32±28.69)points of the cognitive group therapy group were significantly lower than those of the control group,and the difference was statistically significant(t=5.238,P=0.011).The total effective rate of OCD treatment in the cognitive therapy group(97.14%)was significantly higher than that in the control group(74.29%),and the difference was statistically significant(χ^(2)=7.467,P=0.006).After treatment,the HAMD(22.65±4.85)points and HAMA(18.78±4.37)points of the cognitive group therapy group were significantly lower than those of the control group,and the difference was statistically significant(t=6.792,8.408,P<0.05).Conclusion On the basis of antidepressant drug treatment of obsessive-compulsive disorder,the implementation of cognitive-behavioral group therapy has a significant effect on correcting obsessive-compulsive beliefs and negative emotions of patients,which can effectively improve the curative effect,improve its daily symptoms,and improve the quality of life after prognosis.This program has high therapeutic value.