四氢嘧啶的生物大分子保护作用研究进展

Research progress on the protective effect ofectoine on biological macromolecules

四氢嘧啶具有保护生物大分子物质抵抗渗透压改变、高温、冷冻、干燥、辐射等不利环境伤害的作用,对细胞生长无不良影响。但因价格昂贵和保护机制不明确导致应用范围有一定局限性。综述了四氢嘧啶可能的生物大分子保护机制及其研究方法,着重阐述了不利环境条件下四氢嘧啶的保护作用,最后总结了该项研究的必要性并展望了其未来的研究方向。

Ectoine can protect biological macromolecules against adverse environmental damage such as osmotic pressure change,high temperature,freezing,drying and radiation,and has no adverse effect on cell growth.However,due to the high price and unclear protection mechanism,the application scope is limited.Therefore,the possible protection mechanism and research methods of ectoine are reviewed,with emphasis on the protection effect of ectoine under adverse environmental conditions.Finally,the necessity of this research is summarized and its future research direction is prospected.