免疫细胞调控颌骨稳态及损伤修复的研究进展

Advances in the regulation of immune cells in jaw homeostasis and damage repair

颌骨在生命周期中不断地更新重塑,是口颌系统的关键部分。颌骨的稳态和损伤修复受到多种细胞、分子调控。其中,免疫细胞发挥着重要的调控作用。大量研究已证实,免疫系统可以通过多种直接、间接途径调控骨稳态和重塑过程。本文针对免疫细胞调控颌骨稳态和修复的机制进行综述,以期为后续的深入研究提供思路。

The jaw is constantly renewed and remodeled throughout the lifetime and is a crucial part of the stomatognathic system. The jaw homeostasis and repair of jaw injury are regulated by multiple cells and molecules, in which immune cells play an important role. Numerous studies have confirmed that the immune system could regulate the process of bone homeostasis and bone remodeling by direct and indirect pathways. This review summarizes the mechanisms of immune cells regulating bone homeostasis and bone reconstruction in order to provide ideas for future in-depth research.