光热疗法及其协同疗法治疗肝细胞癌的研究进展

Research progress of photothermal therapy and its synergistic therapy in the treatment of hepatocellular carcinoma

原发性肝癌是全球第6大常见癌症和第3大癌症死亡原因,以肝细胞癌为主要发病类型。肝细胞癌发病隐匿,早期无特异性症状,当患者出现临床相关症状时,往往已处于癌症中晚期。因此,大部分患者在确诊时就已经错失了根治性治疗的机会,导致复发率和转移率高、预后效果差。目前肝癌的治疗方法越来越多,光热疗法作为一种新兴的肿瘤治疗方式,因其微创、成本低、效率高、不良反应少和靶向性强等受到人们广泛关注。主要对光热疗法及其协同疗法治疗肝细胞癌的研究进展进行综述,旨在探索肝细胞癌治疗的新思路和策略。

Primary liver cancer is the sixth most commonly diagnosed cancer and the third leading cause of cancer death worldwide,and hepatocellular carcinoma is the main type of primary liver cancer.HCC is insidious and asymptomatic at an early stage,and when clinically relevant,the disease is often in the middle to late stages.As a result,most patients miss out on radical treatment at the time of diagnosis,leading to high recurrence and metastasis rates and poor prognosis.At present,there are more and more methods in the treatment of hepatocellular carcinoma.Photothermal therapy,as an emerging cancer treatment,has attracted widespread attention due to its minimally invasive,low-cost,high efficiency,low side effects and strong targeting.Research progress of photothermal therapy and its synergistic therapy in the treatment of hepatocellular carcinoma were reviewed in this paper,aiming to explore new ideas and strategies for the treatment of hepatocellular carcinoma.