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瘤胃尿素分解菌及脲酶的分子特征与调控研究进展 被引量:1

Research Progress on Ureolytic Bacteria and Molecular Characteristics and Regulation of Urease in Rumen
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摘要 反刍动物瘤胃内尿素分解菌种类多样,探究瘤胃内尿素分解菌组成、了解瘤胃内脲酶活化模式可以为减缓尿素分解速率、提高尿素利用率提供基础。本文综述了基因水平、mRNA水平和蛋白质水平上尿素分解菌的多样性以及高丰度脲酶内辅助蛋白的活化模式,为了解瘤胃内尿素水解过程、针对性开发脲酶抑制剂提供参考。 There are various types of ureolytic bacteria in ruminants.Exploring the composition of ureolytic bacteria and understanding the activation mode of urease in rumen can provide a basis for slowing down urea decomposition rate and improving urea utilization efficiency.The paper reviews the diversity of rumen ureolytic bacteria on the gene level,mRNA level and protein level,respectively,and the activation pattern of auxiliary proteins in rumen high abundance urease,so as to provide a reference for understanding the process of urea hydrolysis in the rumen and developing targeted urease inhibitors.
作者 仲慧月 郑楠 王加启 赵圣国 ZHONG Huiyue;ZHENG Nan;WANG Jiaqi;ZHAO Shengguo(State Key Laboratory of Animal Nutrition,Institute of Animal Science,Chinese Academy of Agricultural Sciences,Beijing 100193,China;Key Laboratory of Quality&Safety Control for Milk and Dairy Products of Ministry of Agriculture and Rural Affairs,Institute of Animal Sciences,Chinese Academy of Agricultural Sciences,Beijing 100193,China;Laboratory of Quality and Safety Risk Assessment for Dairy Products of Ministry of Agriculture and Rural Affairs,Institute of Animal Sciences,Chinese Academy of Agricultural Sciences,Beijing 100193,China)
出处 《动物营养学报》 CAS CSCD 北大核心 2023年第5期2797-2807,共11页 CHINESE JOURNAL OF ANIMAL NUTRITION
基金 内蒙古自治区重点项目(2021-国家乳创中心-2) 动物营养学国家重点实验室(2004DA125184G2108) 中国农业科学院科技创新工程(ASTIP-IAS12) 国家现代农业产业技术体系(CARS-36)。
关键词 瘤胃 尿素分解菌 脲酶活化 rumen ureolytic bacteria urease activation
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