肿瘤基因治疗研究若干新进展
Progress in gene therapy for cancer
摘要
肿瘤是严重危害人类健康的重大疾病,在其发病的分子机制逐渐被人们认识以及基因治疗的措施日趋可行的同时, 肿瘤基因治疗吸引了越来越多的注意。本文就肿瘤免疫基因治疗、抑癌基因治疗、诱导凋亡基因治疗及载体靶向性研究等方 面的研究进展作一综述。
出处
《第二军医大学学报》
CAS
CSCD
北大核心
2002年第11期1258-1260,共3页
Academic Journal of Second Military Medical University
参考文献17
-
1[1]http://www.wiley.co.uk/genmed.
-
2[2]Liu Y,Ehtesham M,Samoto K,et al.In situ adenoviral interleukin 12 gene transfer confers potent and long-lasting cytotoxic immunity in glioma[J].Cancer Gene Ther,2002,9(1):9-15.
-
3[3]Wang Z,Qiu SJ,Ye SL,et al.Combined IL-12 and GM-CSF gene therapy for murine hepatocellular carcinoma[J].Cancer Gene Ther,2001,8(10):751-758.
-
4[4]Osaki T,Peron JM,Cai Q,et al.IFN-gamma-inducing factor/IL-18 administration mediates IFN-gamma- and IL-12-independent antitumor effects[J].J Immunol,1998,160(4):1742-1749.
-
5[5]Oshikawa K,Shi F,Rakhmilevich AL,et al.Synergistic inhibition of tumor growth in a murine mammary adenocarconoma model by combinational gene therapy using IL-12,pro-IL-18,and IL-1β converting enzyme cDNA[J].Proc Nat Acad Sci USA,1999,96(23):13351-13356.
-
6[6]Sun X,Kanwar JR,Leung E,et al.Angiostatin enhances B7.1-mediated cancer immunotherapy independently of effects on vascular endothelial growth factor ex presion[J].Cancer Gene Ther,2001,8(10):719-727.
-
7[7]Niederman TM,Ghogawala Z,Carter BS,et al.Antitumor activity of cytotoxic T lymphocytes engineered to target vascular endothelial growth factor receptors[J].Proc Natl Acad Sci USA,2002,99(10):7009-7014.
-
8[8]Nishizaki M,Fujiwara T,Tanida T,et al.Recombinant adenovirus expression wild-type p53 is antiangiogenic: a proposed mechanism for bystander effect[J].Clin Cancer Res,1999,5(5): 1015-1023.
-
9[9]Yu JL,Rak JW,Coomber BL,et al.Effect of p53 status on tumor response to antiangiogenic therapy[J].Science,2002,295(5559):1526-1528.
-
10[10]Seki M,Iwakawa J,Cheng H,et al. p53 and PTEN/MMAC1/TEP1 gene therapy of human prostate PC-3 carcinoma xenograft,using transferrin-facilitated lipofection gene delivery strategy[J].Hum Gene Ther,2002,13(6):761-773.
-
1张昌菊.肿瘤免疫基因治疗[J].实用医学进修杂志,1995,23(4):247-249.
-
2沈裕康.肿瘤的基因治疗[J].上海医药,1999,20(9):11-13.
-
3陆前进.恶性黑素瘤基因治疗的研究进展[J].国外医学（皮肤性病学分册）,1997,23(6):329-331.
-
4梁中骁.肝癌的基因治疗[J].中国医学文摘（肿瘤学）,2003,17(3):269-271.
-
5曹海利,孟巍,白彬.肝癌基因治疗研究新进展[J].介入放射学杂志,2008,17(5):375-378. 被引量：5
-
6刘宏旭,许顺,赵惠儒,殷洪年.肺癌的基因治疗[J].中华结核和呼吸杂志,1999,22(5):305-307. 被引量：6
-
7陆东东.肝癌基因治疗研究进展[J].实用肝脏病杂志,1997,2(1):48-49.
-
8人类抑癌基因治疗小鼠胃癌[J].国际医药卫生导报,2001,7(07B):35-35.
-
9潘海涛,杨述华.骨肉瘤基因治疗的研究进展[J].国外医学（骨科学分册）,2004,25(3):143-146. 被引量：1
-
10肖农,曹雪涛.肝癌的基因治疗研究进展[J].国外医学（肿瘤学分册）,1996,23(1):56-59. 被引量：2
