基于β-环糊精的电化学手性传感器的制备及应用

Synthesis and application of electrochemical chiralsensor based onβ-cyclodextrin

以β-环糊精(β-CD)为手性选择剂、多壁碳纳米管(MWCNTs)为导电吸附剂、铂纳米粒子(PtNPs)为电子转移导体,制备了电化学传感器β-CD-PtNPs-RCNTs,并通过透射电子显微镜(TEM)、循环伏安法(CV)和交流阻抗对其进行了表征。由于β-环糊精特有的空间结构和多壁碳纳米管的优良导电性,手性传感平台在循环伏安法(CV)实验中对2-氨基-1-(4-硝基苯基)-1,3-丙二醇对映体表现出良好的识别效果。同时,该传感装置通过电化学测试表现出良好的稳定性和重复性。本研究为构建基于吸附原理的手性传感平台提供了另一种方法。

An electrochemical chiralsensor(β-CD-PtNPs-RCNTs)was constructed via chiral selectorβ-cyclodextrin(β-CD),adsorbent multi-walled carbon nanotubes(MWCNTs)and platinum nanoparticles(PtNPs).The material has been characterized by transmission electron microscopy(TEM),cyclic voltammetry(CV)and AC impedance method.Moreover,the superior conductivity of MWCNTs and the decent spatial structure ofβ-cyclodextrin endowed this sensing platform with excellent recognition effect for 2-amino-1-(4-nitrophenyl)-1,3-propanediol enantiomers in the differential cyclic voltammetry(CV)test.The sensing device displayed considerable stability and superior repeatability in the electrochemical tests.This may manifest an alternative method of chiral sensing plat-form based on adsorption principle.