急性冠状动脉综合征眼部表现研究现状与进展

The research status and progress of ocular manifestations related to acute coronary syndromes

急性冠状动脉综合征(ACS)是由冠状动脉粥样硬化斑块不稳定或破裂引起的临床综合征。ACS的发生、发展及其治疗与眼部表现密切相关。高血压视网膜病变、视网膜动静脉阻塞、糖尿病视网膜病变、老年性黄斑变性等与较高的ACS发病风险相关。视网膜血管阻塞可能是ACS经皮冠状动脉介入治疗后的潜在并发症。视网膜血管直径及血管密度、眼动脉血流速度、脉络膜厚度等眼部参数有望成为评估或预测ACS风险的标志物,对于ACS等心血管事件的预防具有重要价值。

Acute coronary syndromes(ACS)are clinical syndromes caused by the instability or rupture of coronary atheromatous plaques.The development and treatment of ACS are closely related to some ocular manifestations.Hypertensive retinopathy,retinal arteriovenous occlusion,diabetes retinopathy,and age-related macular degeneration are associated with a high risk of ACS.Retinal vascular occlusion may be a potential postoperative complication of the percutaneous coronary intervention for ACS.Ocular parameters such as the retinal vascular diameter and density,the blood flow velocity of the ophthalmic artery,and the choroidal thickness are expected to be markers for assessing or predicting the risk of ACS,which are of important value for the prevention of cardiovascular events such as ACS.