阿托伐他汀辅助钻孔引流术治疗慢性硬膜下血肿的效果

Effect of Atorvastatin Assisted Drilling Drainage in the Treatment of Chronic Subdural Hematoma

目的:探讨阿托伐他汀联合钻孔引流术治疗慢性硬膜下血肿患者的临床有效性与安全性。方法:选取2019年12月—2022年5月我院收治的慢性硬膜下血肿患者88例作为研究对象,根据1∶1电脑随机分配原则分为阿托伐他汀组44例与对照组44例。对照组给予钻孔引流术治疗,阿托伐他汀组在对照组治疗基础上给予阿托伐他汀治疗,比较两组临床指标、临床疗效、神经功能及日常生活能力。结果:阿托伐他汀组症状消失时间快于对照组,总引流量、引流时间、住院时间低于对照组(P<0.05);阿托伐他汀组治疗4周后的总有效率为97.73%,高于对照组的86.36%(P<0.05);阿托伐他汀组CSS神经功能评分低于对照组,ADL日常生活能力评分高于对照组(P<0.05)。结论:阿托伐他汀联合钻孔引流术治疗慢性硬膜下血肿患者的效果确切,能缩短症状消失时间、总引流量、引流时间与住院时间,改善患者的神经功能与日常生活能力,降低并发症发生率。

Objective:To investigate the clinical efficacy and safety of atorvastatin combined with drilling drainage in the treatment of patients with chronic subdural hematoma.Methods:Eighty-eight patients with chronic subdural hematoma admitted to our hospital from December 2019 to May 2022 were selected as the research objects.According to the principle of 1:1 computer random distribution,they were divided into atorvastatin group(44 cases) and control group(44 cases).The control group was treated with drilling drainage,and the atorvastatin group was treated with atorvastatin on the basis of the control group.The clinical indexes,clinical efficacy,neurological function and daily living ability of the two groups were compared.Results:The disappearance time of symptoms in the atorvastatin group was faster than that in the control group,and the total drainage volume,drainage time and hospitalization time were lower than those in the control group(P<0.05).The total effective rate of atorvastatin group after 4 weeks of treatment was 97.73%,which was higher than 86.36% of control group(P<0.05).CSS neurological function score of atorvastatin group was lower than that of control group,and ADL daily living ability score was higher than that of control group(P<0.05).Conclusion:Atorvastatin combined with drilling drainage is effective in the treatment of patients with chronic subdural hematoma,which can shorten the time of symptom disappearance,total drainage volume,drainage time and hospitalization time,improve the neurological function and daily living ability of patients,and reduce the incidence of complications.