武汉市某高校诺如病毒引起的食源性胃肠炎暴发

foodborne gastroenteritis outbreak caused by Norovirus in a university of Wuhan

目的分析2021年12月武汉某高校一起由诺如病毒引起的食源性胃肠炎暴发的流行病学因素,为制定防控措施提供科学依据。方法开展现场流行病学调查,采用描述性流行病学方法、病例对照研究方法对导致事件发生的危险因素进行分析,并采集病例直肠拭子及环境样本进行病原学检测。结果病例共139例,患病率为0.43%,临床症状主要为恶心、呕吐、腹泻。食用H街卤菜是危险暴露因素[比值比(OR)=15.96,95%置信区间(95%CI):2.32~383.95]。29名病例及5名从业人员检出诺如病毒GⅡ型。结论此次事件为一起由诺如病毒GⅡ型引起的食源性胃肠炎暴发。在诺如病毒感染高发季节,应继续加强对学校及食品从业人员的诺如病毒感染监测,积极开展食品卫生方面的健康教育,预防肠道病原体感染暴发发生。

Objective To provide scientific basis for formulating prevention and control measures,the epidemiological factors of an foodborne gastroenteritis outbreak caused by Norovirus in a university of Wuhan in December 2021 were analyzed.Methods The field epidemiological method was used to investigate.The risk factors leading to the event were studied by descriptive epidemiological method and case-control method.Anal swabs and environmental samples were collected for pathogenic detection.Results One hundred and thirty nine cases were identified,with an attack rate of 0.43%.The main clinical symptoms were nausea,vomiting and diarrhea.Eating H Street pickles was a risk exposure factor(OR=15.96,95%CI:2.32-383.9).Twenty nine cases and 5 food practitioners were positive for Norovirus GⅡ.Conclusion The foodborne gastroenteritis outbreak was caused by Norovirus GⅡ.In the season of high incidence of Norovirus infection,the monitoring of norovirus infection should be strengthened in schools and food practitioners,and health education of food hygiene should be carried out actively to prevent the outbreak of intestinal pathogen infection.