2015—2020年临沂市常见消化系统恶性肿瘤早死概率与早死寿命损失分析

Analysis of probability of and years of life lost from premature mortality due to common cancers of digestive system in Linyi,2015-2020

目的 了解2015—2020年临沂市常见消化系统恶性肿瘤早死概率、早死寿命损失及变化趋势,为制定相应的防控措施提供数据支撑。方法 对2015—2020年临沂市全人群死因监测资料进行数据分析,采用SAS 9.2软件计算临沂市常见消化系统恶性肿瘤粗死亡率、标化死亡率、早死概率、早死寿命损失及年度变化百分比(annual percent change,APC)。结果 2015—2020年临沂市常见消化系统恶性肿瘤整体粗死亡率和标化死亡率分别为64.66/10万、50.39/10万;其中男性分别为89.97/10万、73.07/10万;女性分别为37.46/10万、27.24/10万。临沂市常见消化系统恶性肿瘤早死概率由2015年2.95%下降至2020年2.66%,APC为-2.40%(P<0.05);其中,肝癌、胃癌和食管癌早死概率呈下降趋势,APC分别为-3.80%、-4.20%和-3.80%(P<0.05);胰腺癌早死概率呈上升趋势,APC为8.60%(P<0.05)。2015—2020年临沂市常见消化系统恶性肿瘤造成的整体寿命损失年(years of life lost,YLL)和寿命损失年率(years of life lost rate,YLLR)分别为378 028.23人年、10.63年/千人;其中,肝癌的YLLR和胃癌的YLL、YLLR呈下降趋势,APC分别为-3.20%、-2.40%和-3.60%(P<0.05);结直肠癌和胰腺癌的YLL、YLLR均呈上升趋势,APC分别为5.60%、4.20%、10.20%和8.90%(P<0.05)。结论 临沂市常见消化系统恶性肿瘤引起的死亡率处于较高水平,尤其是结直肠癌和胰腺癌引起的死亡率、早死概率和早死寿命损失呈上升趋势,应加强该地区消化系统恶性肿瘤防治工作。

Objective To analyze the probability of and years of life lost(YLL)from premature mortality due to common cancers of digestive system and their time trends in Linyi city in the period from 2015 to 2020,so as to provide evidence for cancer prevention and control measures.Methods Death surveillance data from 2015 to 2020 in Linyi were analyzed.SAS 9.2 software was use to calculate crude mortality rate,standardized mortality rate,premature mortality probability,years of life lost(YLL)from premature mortality and annual percent change(APC)for common cancers of digestive system.Results The overall crude mortality rate and the standardized mortality rate of common cancers of digestive system in Linyi from 2015 to 2020 were 64.66/105 and 50.39/105,respectively,with the features being 89.97/105 and 73.07/105 in males,and 37.46/105 and 27.24/105 in females.The probability of premature death from common gastrointestinal cancers in Linyi decreased from 2.95%in 2015 to 2.66%in 2020,its APC being−2.40%(P<0.05).The decreasing trend was also observed in liver,stomach,and esophageal cancers,with the APC being−3.80%,−4.20%and−3.80%(P<0.05),respectively;whereas an increasing trend of premature death was observed in pancreatic cancer,with the APC being 8.6%(P<0.05).The YLL and years of life lost rate(YLLR)from 2015 to 2020 from common cancers of digestive system in Linyi were 378028.23 person-years and 10.63 years per thousand person,respectively.The YLLR in liver cancer,and the YLLR and YLL in stomach cancer declined,their APC were−3.2%,−2.4%and−3.6%,respectively;whiles the YLL and YLLR in colorectal cancer and pancreatic cancer increased,with APC being 5.6%,4.2%,10.2%and 8.9%,respectively(P<0.05).Conclusions The mortality caused by common cancers of the digestive system in Linyi continues to be at a high level.In particular,the mortality rate,the probability of premature death and the years of life lost due to colorectal cancer and pancreatic cancer are on the rise.Prevention of and treatment for gastrointestinal cancers should be strengthened in this area.