云南省暗娼人群生殖道沙眼衣原体和淋球菌感染现状及影响因素分析

Prevalence and influencing factors of Chlamydia trachomatis and Neisseria gonorrhoeae infections among female sex workers in Yunnan Province

目的了解云南省暗娼人群生殖道沙眼衣原体(Chlamydia trachomatis,CT)和淋球菌(Neisseria gonorrhoeae,NG)感染的流行现状及相关影响因素。方法2021年1—6月,对云南省16个州(市)的暗娼人群共2627人进行现场问卷调查,并采集尿液样本进行核酸检测。结果云南省暗娼人群的CT感染率为14.4%(379/2627),NG感染率为3.6%(94/2627),CT和NG混合感染率为2.2%(59/2627)。多因素Logistic回归分析表明,滇东南地区(OR=3.225,95%CI:1.946~5.345)、≤25岁(OR=2.411,95%CI:1.579~3.681)、在本地工作1~<6个月(OR=1.658,95%CI:1.216~2.261)、最近一年被诊断出性病(OR=7.558,95%CI:4.017~14.221)是暗娼CT感染危险因素;滇东南地区(OR=3.219,95%CI:1.232~8.411)、少数民族(OR=1.982,95%CI:1.238~3.172),以及在本地工作<1个月(OR=1.945,95%CI:1.060~3.571)是暗娼NG感染的危险因素。结论云南省暗娼人群CT和NG感染率较高,滇东南地区、年龄≤25岁的本地工作人员易感染CT,而滇东南地区的少数民族群体易感染NG。应对暗娼人群持续进行健康教育并增加干预频次,避免重复感染带来不良的健康结局。

Objective To investigate the prevalence and influencing factors of Chlamydia trachomatis(CT)and Neisseria gonorrhoeae(NG)infections among female sex workers in Yunnan Province.Methods From January to June,2021,a total of 2627 female sex workers from 16 prefectures in Yunnan Province were surveyed with on-site questionnaires and urine samples were collected for nucleic acid testing.Results The infection rates of CT and NG in female sex workers in Yunnan were 14.4%(379/2627)and 3.6%(94/2627),respectively.The co-infection rate of CT and NG was 2.2%(59/2627).The multivariate Logistic regression analysis showed that living in southeast Yunnan(OR=3.225,95%CI:1.946-5.345),aged≤25 years(OR=2.411,95%CI:1.579-3.681),working locally for 1-<6 months(OR=1.658,95%CI:1.216-2.261),and diagnosis with sexually transmitted diseases in the last year(OR=7.558,95%CI:4.017-14.221)were the risk factors for CT infection in female sex workers.Living in southeast Yunnan(OR=3.219,95%CI:1.232-8.411),ethnic minorities(OR=1.982,95%CI:1.238-3.172)and working locally for less than one month(OR=1.945,95%CI:1.060-3.571)were the risk factors for NG infection in female sex workers.Conclusions The female sex workers in Yunnan Province have a high prevalence of CT and NG.Local workers living in southeast Yunnan and aged≤25 years are susceptible to CT,while ethnic minorities living in southeast Yunnan are susceptible to NG.It is necessary to continuously carry out health education and increase the frequency of intervention,so as to avoid adverse health outcomes caused by re-infection.