醒脑开窍针刺联合普瑞巴林治疗卒中后丘脑痛100例临床观察

Clinical observation on 100 cases of post stroke thalamic pain treated with consciousness-restoring resuscitation acupuncture combined with pregabalin

目的 观察醒脑开窍针刺联合普瑞巴林治疗卒中后丘脑痛的临床疗效。方法 将200例卒中后丘脑痛患者采用随机数字表法分为对照组和治疗组,各100例。对照组予普瑞巴林口服,治疗组在对照组治疗方法的基础上予醒脑开窍针刺治疗,连续治疗8周后比较2组的临床疗效以及治疗前后的视觉模拟评分法(VAS)评分、临床症状积分、匹兹堡睡眠质量指数(PSQI)评分、生活质量评分。结果 治疗组总有效率为98%(98/100),对照组为89%(89/100),2组比较差异有统计学意义(P<0.01);治疗后2组VAS评分、临床症状积分、PSQI评分均明显降低,生活质量评分明显升高,与同组治疗前比较差异有统计学意义(P<0.01),且治疗组改善更明显,与对照组治疗后比较差异均有统计学意义(P<0.01)。结论 醒脑开窍针刺联合普瑞巴林治疗卒中后丘脑痛疗效显著,可明显改善患者的临床症状,提高睡眠及生活质量。

Objective To observe the clinical efficacy of consciousness-restoring resuscitation acupuncture combined with pregabalin in the treatment of post stroke thalamic pain.Methods 200 patients with post stroke thalamic pain were randomly divided into a control group and a treatment group with 100 patients each. The control group was treated with oral pregabalin, and the treatment group was treated with consciousness-restoring resuscitation acupuncture based on the treatment method in the control group. After 8 weeks of continuous treatment, the clinical efficacy, visual analogue scale(VAS) scores, clinical symptom scores, Pittsburgh sleep quality index(PSQI) scores, and life quality scores of the two groups were compared before and after treatment.Results The total effective rate was 98%(98/100) in the treatment group and 89%(89/100) in the control group, with a statistically significant difference between the two groups(P<0.01). After treatment, the VAS score, clinical symptom score, and PSQI score in the two groups were significantly reduced, while the life quality scores were significantly increased, with a statistically significant difference compared to the same group before treatment(P<0.01).Moreover, the improvement in the treatment group was more significant, with a statistically significant difference compared to the control group after treatment(P<0.01).Conclusion Consciousness-restoring resuscitation acupuncture combined with pregabalin has a significant effect on the treatment of post stroke thalamic pain, which can significantly improve the clinical symptoms, sleep, and life quality of patients.