早中期帕金森病患者运动管理的最佳证据总结

Best evidence summary for exercise management for patients in early and middle stage of Parkinson’s disease

目的检索汇总早中期帕金森病患者运动管理的相关证据,并总结最佳证据,为指导早中期帕金森病患者运动锻炼提供依据。方法确定循证问题,计算机检索UpToDate、JBI、BMJ、NGC、NICE、RNAO、GIN、Cochrane Library、PubMed、Web of Science、Embase、PEDro、中国知网、万方数据库、维普数据库、中国生物医学文献服务网及美国帕金森病协会、美国物理治疗协会网站,由2名研究员对文献质量进行评价,并对符合质量标准的文献进行证据提取。结果共纳入18篇文献,其中指南4篇、专家意见2篇、系统评价11篇、质性系统评价1篇。分析总结后提取了包括运动时机、运动评估与测试、运动实施、运动安全、健康教育、效果评价6个方面的29条项目。结论本研究总结早中期帕金森病患者运动管理的相关证据,运动可改善帕金森的症状,医护人员需依据评估结果,参考患者的实际情况,进行个性化运动指导,以期延缓疾病进展,提高生活质量。

Objective To retrieve and summarize the best evidence for exercise management for patients in the early and middle stage of Parkinson’s disease and to provide exercise guidance for patients with Parkinson’s disease.Methods Evidence-based problems were identified and we searched UpToDate,JBI,BMJ,NGC,NICE,RNAO,GIN,Cochrane Library,PubMed,Web of Science,Embase,PEDro,CNKI,Wanfang Data,VIP,CBM,APDA and APTA for eligible literature.Two researchers independently appraised articles and extracted data.Results A total of 18 articles were eligible,including 4 guidelines,2 expert consensuses,11 systematic reviews and 1 systematic review,and 29 pieces of evidence were summarized into 6 aspects:exercise timing,assessment and testing,exercise implementation,safety,health education and effect evaluation.Conclusion Exercise can alleviate symptoms of Parkinson’s disease.Personalized exercise programs for patients in accordance with the assessment and the situation of patients are conducive to slowing down the disease progression and improving the quality of life.