高风险脱机患者高流量氧疗与低频持续气道正压通气效果比较

Comparison of the clinical effects of high-flow oxygen therapy and low-frequency continuous positive airway pressure ventilationin patients with high risk of weaning

目的探讨高风险脱机患者使用高流量氧疗(HFNC)和低频持续气道正压通气(CPAP)临床效果的优劣性,避免或缩短无效氧疗支持时间。方法将符合常规脱机程序但至少具有一种高风险脱机因素的患者随机分为CPAP组(69例)和HFNC组(71例),CPAP组行CPAP治疗,HFNC组行HFNC治疗,在相同医疗和护理条件下观察48 h。结果HFNC组患者呼吸频率,24 h、48 h时患者疼痛得分低于CPAP组(均P<0.05)。结论在高风险脱机患者中采用HFNC更能改善患者的呼吸、降低其疼痛感。

Objective To compare the clinical effects of high-flow Nasal Cannula oxygen therapy and low-frequency continuous positive airway pressure ventilation in patients at high risk of weaning and to avoid or shorten the supporting time of in effective oxygen therapy.Methods Patients who met routine weaning procedures and had at least one high risk factor for weaning were randomly assigned to CPAP group(n=69)or HFNC group(n=71),CPAP group received CPAP therapy,HFNC group received HFNC therapy,observed for 48 h under the same medical and nursing conditions.Results The respiratory frequency and pain scores of patients in HFNC group were lower than those in CPAP group at 24 h and 48 h(P<0.05).Conclusion HFNC can improve breathing and reduce pain in patients at high risk of weaning.