阿奇霉素联合布地奈德混悬液与沙丁胺醇雾化吸入治疗小儿支原体肺炎的效果及安全性

Effect and safety of Azithromycin and Budesonide Suspension and Salbutterol inhalation in the treatment of pediatric Mycoplasma pneumonia

目的探讨在小儿支原体肺炎治疗中联合阿奇霉素、布地奈德混悬液与沙丁胺醇雾化吸入的效果。方法选取2020年5月至2022年12月涟水县人民医院收治的83例支原体肺炎患儿,按照随机数字表法进行分组。对照组41例采用阿奇霉素治疗,研究组42例在对照组基础上联合布地奈德混悬液与沙丁胺醇雾化吸入治疗。观察两组患儿临床效果、症状改善时间、住院时间以及用药后不良反应。结果研究组患儿治疗总有效率较对照组高(P<0.05)。研究组退热时间、咳嗽缓解时间、憋喘改善时间、肺啰音消失时间以及住院时间均短于对照组(P<0.05)。研究组与对照组不良反应总发生率比较,差异无统计学意义(P>0.05)。结论在小儿支原体肺炎治疗中联合应用阿奇霉素、布地奈德混悬液与沙丁胺醇雾化吸入的疗效可靠,可缩短患儿症状改善时间,且不会增加患儿用药后的不良反应,值得推广。

Objective To investigate the effect of Azithromycin and Budesonide Suspe nsion and Salbutterol inhalation in the treatment of pediatric Mycoplasma pneumonia.Methods A total of 83 cases of children with Mycoplasma pneumonia admitted to Lianshui County People’s Hospital from May 2020 to December 2022 were selected and grouped according to the random number table method.41 cases in the control group were treated with Azithromycin,and 42 cases in the study group were treated with Budesonide Suspension combined with Salbutamol inhalation on the basis of the control group.The clinical effects,symptom improvement time,hospitalization time and adverse reactions after medication were observed in the two groups.Results The total effective rate of treatment in the study group was higher than that in the control group(P<0.05).The time to fever withdrawal,cough relief,wheezing improvement,lung rale disappearance and hospital stay in the study group were shorter than those in the control group(P<0.05).There was no difference in the total incidence of adverse reactions between the study group and the control group(P>0.05).Conclusion In the treatment of Mycoplasma pneumonia in children,the combination of Azithromycin,Budesonide Suspension and Salbutamol inhalation has ideal effect,can shorten the improvement time of symptoms of children,and will not increase the adverse reactions of children after medic ation,which is worth popularizing.