河南省HIV暴露婴儿早期诊断检测情况分析

Study of early diagnosis and detection for HIV exposed infants in Henan province

目的 探明河南省2015—2020年HIV暴露婴儿早期诊断检测情况,为改进河南省HIV早期诊断工作提供参考依据。方法 对2015年至2020年期间送检至郑州大学第三附属医院的婴儿早期诊断样本数据进行回顾性统计分析。结果 研究期间HIV暴露婴儿阳性检出率为2.67%,并呈逐年下降趋势,由2015年的9.52%降至2020年的1.81%。2015年至2020年期间,暴露婴儿出生42天第一次采集率由54.76%上升至83.13%,差异有统计学意义(χ^(2)=19.46,P<0.05);90天第二次采集率由55.56%上升至85.81%,差异有统计学意义(χ^(2)=7.61,P<0.05);从样本送检到结果报告,周期呈现缩短趋势,差异有统计学意义(χ^(2)=67.50,P<0.05)。结论 河南省HIV暴露婴儿母婴传播率逐年下降,河南HIV婴儿早期诊断区域实验室运行良好。

Objective To ascertain the early diagnosis and detection of HIV-exposed infants in Henan Province from 2015 to 2020,and to provide a reference basis for improving the early diagnosis of HIV in Henan Province.Methods This study conducted a retrospective statistical analysis on the result of early diagnosis of HIV exposed infants from 2015 to 2020.Results The sample collection rate increased during the study period.The first collection rate increased from 54.76% to 83.13% within 42 days(χ^(2)=19.46,P<0.05),and the second collection rate increased from 55.56% to 85.81% within 90 days(χ^(2)=7.61,P<0.05).The period from sample submission to result report showed a downward trend(χ^(2)=67.50,P<0.05);During the study period,the mother to child transmission rate was 2.67%,and the mother to child transmission rate decreased from 9.52% in 2015 to 1.81% in 2020.Conclusion The samples submitted for early diagnosis of HIV exposed infant in Henan Province are increased from 2016 to 2020.The sample collection times and the proportion of samples collected corresponding to the age of month are also increased.The time required for sample operation and report issuance are reduced.The above results shows that the regional laboratory for early infant diagnosis of HIV exposed infant established in Henan province runs well.