恶性腹膜间皮瘤1例

A case of malignant peritoneal mesothelioma

恶性间皮瘤是一种高度恶性的疾病,最常发生在胸膜,其次是腹膜、心包等。恶性腹膜间皮瘤(MPM)占所有间皮瘤的10%~15%,石棉接触是其最重要的风险因素。MPM没有特定的临床症状,影像学和组织病理学检查对诊断非常重要。目前,MPM尚没有普遍接受的根治性治疗指南;本例患者主要表现为腹痛、腹胀不适,由于大网膜广泛转移,未行进一步手术治疗,给予培美曲塞联合顺铂方案化疗2周期后,患者存活已超过2年。

Malignant mesothelioma is a highly malignant disease that most often occurs in the pleural cavity,followed by the peritoneum and pericardium.Malignant peritoneal mesothelioma(MPM)accounts for 10%-15%of all mesothelioma.The most important risk factor for MPM is exposure to asbestos.MPM has no specific clinical symptoms,imaging and histopathology are critical for the diagnosis.There are currently no generally accepted guidelines for curative treatment of MPM.The patient mainly presented with abdominal pain,abdominal distension and discomfort.Due to extensive omentum metastasis,no further surgical treatment was performed.Pemetrexed combined with cisplatin chemotherapy was given for 2 cycles,and the patient is still alive.