农药敌草快中毒引发迟发性周围神经病变1例

A case of delayed peripheral neuropathy caused by diquat poisoning

敌草快为传导性触杀灭生性除草剂,中枢神经系统损害相对多见,引起周围神经病变尚无报道。2021年9月山东大学齐鲁医院德州医院收治1例敌草快中毒患者,住院治疗期间患者出现周围神经病变,在常规治疗中毒的基础上给予营养周围神经治疗,患者整体病情稳定后出院。门诊随访患者周围神经病变情况日益好转。该病例提示在临床工作中对于敌草快中毒不仅需要及早对胃肠道、肝肾、中枢神经系统的功能保护,亦不可忽视周围神经病变的可能性,应及早干预,改善患者预后。

Diquat is a kind of conductive contact-killing herbicides.The damage of central nervous system is relatively common,but the peripheral neuropathy caused by diquat has not been reported yet.In September 2021,we treated a patient with diquat poisoning.During the hospitalization,the patient was diagnosed with peripheral neuropathy.Therapy for peripheral nerve injury was given on the basis of conventional treatment of poisoning.The patient was discharged after his condition was stable.The follow-up showed that the peripheral neuropathy of patient was better than before.According to the condition of this patient,it is suggested that we should not only protect the function of gastrointestinal tract,liver,kidney,and central nervous system early,but should also pay attention to the damage of peripheral nervous system in clinical work.We should intervene earlier to improve the prognosis of patients.