阿奇霉素联合特布他林治疗肺炎支原体肺炎患儿的效果及对睡眠质量的影响

Effect of Azithromycin Combined with Terbutaline in the Treatment of Children with Mycoplasma Pneumoniae Pneumonia and its Effect on Sleep Quality

目的:探讨阿奇霉素联合特布他林治疗肺炎支原体肺炎(MPP)患儿的效果及对睡眠质量的影响。方法:将2020年6月至2021年6月丰泽区妇幼保健院收治的100例MPP患儿,按随机数字表法分为对照组和观察组,每组50例。对照组予以阿奇霉素治疗,观察组则予以阿奇霉素联合特布他林雾化吸入治疗。比较2组的症状缓解时间及住院天数、炎症水平、睡眠质量。结果:观察组的各症状缓解时间及住院天数均短于对照组(P<0.05)。治疗后观察组的IL-6、PCT、CRP水平低于对照组(P<0.05)。治疗后观察组的PSQI量表得分低于对照组(P<0.05),睡眠改善时间短于对照组(P<0.05)。结论:阿奇霉素联合特布他林可有效降低MPP患儿机体的炎症,促进疾病症状缓解,并改善睡眠质量,缩短住院时间。

Objective:To investigate the effect of azithromycin combined with terbutaline in the treatment of children with Mycoplasma pneumoniae pneumonia(MPP)and its effect on sleep quality.Methods:A total of 100 children with MPP who were admitted to our hospital from June 2020 to June 2021 were included and divided into control group and observation group according to the random number table method,with 50 cases in each.Control group was treated with azithromycin,and observation group was treated with azithromycin combined with terbutaline inhalation.The symptom relief time,length of hospital stay,inflammation level,and sleep quality were compared between the two groups.Results:The symptom relief time and hospitalization days in observation group were shorter than those in control group(P<0.05).The levels of interleukin-6(IL-6),procalcitonin(PCT)and C-reactive protein(CRP)of observation group were lower than those of control group(P<0.05).After treatment,the Pittsburgh Sleep Quality Index(PSQI)score of observation group was lower than that of control group,and the sleep improvement time was shorter than that of control group(P<0.05).Conclusion:Azithromycin combined with terbutaline can effectively reduce inflammation in children with MPP,promote disease symptom relief,improve sleep quality,and shorten hospital stay.