影像学在脑小血管病血流动力学方面的研究进展

Advances in the study of imaging in the hemodynamics of cerebral small vessel disease

脑小血管病(CSVD)是指各种病因影响颅内小动脉、微动脉、毛细血管、微静脉和小静脉所导致的一系列临床、影像和病理学综合征。越来越多的研究结果显示,CSVD与颅内动脉血流动力学参数的变化密切相关。本文就CSVD的流行病学、病因及发病机制、形态学诊断、功能学诊断进行综述。以期为CSVD病因及发展机制的研究提供思路及依据,并有助于监测CSVD患者的病情变化,尽早临床干预治疗,从而提高患者预后,改善生活质量。

Cerebral small vessel disease(CSVD)is a series of clinical,imaging and pathological syndromes resulting from various etiologies affecting small intracranial arteries,microarteries,capillaries,microvenules and small veins.A growing number of findings have shown that CSVD is closely associated with changes in intracranial arterial hemodynamic parameters.In this article,we review the epidemiology,etiology and pathogenesis,morphological diagnosis,and functional diagnosis of CSVD.It is expected to provide ideas and basis for research on the etiology and development mechanism of CSVD,and to help monitor the changes of CSVD patients’conditions and early clinical interventions for treatment,thus improving patients’prognosis and quality of life.