CCBT-I对妊娠中期失眠孕妇睡眠质量及T淋巴细胞亚群水平的影响

Effect of CCBT-I on sleep quality and T lymphocyte subsets of insomnia pregnant women in the second trimester of pregnancy

目的分析计算机化认知行为治疗(CCBT-I)对妊娠中期失眠孕妇睡眠质量及T淋巴细胞亚群的影响。方法选择2020年10月至2022年8月该院产科门诊接诊的妊娠中期失眠孕妇60例作为研究对象,采用随机数字表法分为对照组(常规干预)和研究组(给予CCBT-I),每组30例。评估对比两组孕妇干预前及干预后睡眠质量、失眠严重程度、嗜睡程度、抑郁及焦虑情况等,并进行血清T淋巴细胞亚群检测。结果研究组孕妇干预后失眠严重程度指数、匹兹堡睡眠质量指数、雅典失眠量表、爱泼沃斯嗜睡量表、状态-特质焦虑问卷、贝克抑郁量表评分均低于对照组,CD3^(+)、CD4^(+)T淋巴细胞水平均高于对照组,差异均有统计学意义(P<0.05)。结论给予妊娠中期失眠孕妇CCBT-I可明显改善其睡眠质量,缓解其抑郁和焦虑情绪,提高孕妇免疫力。

Objective To analyze the effect of computerized cognitive behavioral therapy(CCBT-I)on sleep quality and T lymphocyte subsets of insomnia pregnant women in the second trimester of pregnancy.Methods A total of 60 pregnant women with insomnia in the second trimester of pregnancy admitted to the obstetrics clinic of this hospital from October 2020 to August 2022 were selected and divided into the control group(routine intervention)and the experimental group(given CCBT-I)by using the random number table method,with 30 cases in each group.The sleep quality,insomnia severity,sleepiness degree,depression and anxiety of pregnant women of the two groups before and after intervention were evaluated and compared,and the serum T lymphocyte subsets were detected.Results After intervention,the scores of insomnia severity index,Pittsburgh sleep quality index,Athens insomnia scale,Epworth sleepiness scale,State-trait Anxiety Questionnaire and Beck depression scale in pregnant women of the experimental group were significantly lower than those in the control group,CD3^(+)and CD4^(+)T lymphocyte cells levels in the experimental group were higher than those in the control group,and the differences were statistically significant(P<0.05).Conclusion The administration of CCBT-I to insomnia pregnant women in the second trimester of pregnancy can significantly improve their sleep quality,alleviate depression and anxiety,and can improve the immunity of pregnant women.