间质性肺病继发感染的研究进展

Study on secondary infections based on interstitial lung disease

间质性肺病(ILD)是因临床表现、胸部影像学和病理特征相似而被归为一类的疾病,其特点是肺间质内的炎症或纤维化。ILD基础上的继发感染会增加ILD患者的病死率,因为定植菌群的存在以及隐性感染的可能,尽管诊断方法有所进步,但部分感染相关病原体仍难以临床确诊。

Interstitial lung disorders(ILD)are a category of illnesses defined by inflammation or fibrosis in the interstitial lung that share clinical,radiological,and pathological characteristics.Despite advancements in diagnostic technologies,several infection-associated organisms remain difficult to identify clinically due to the existence of colonized flora and the possibility of concealed illness.In this review,we discuss the pathophysiology of secondary infections in the context of ILD,as well as the most prevalent infections that occur.