石斛生物碱抗肿瘤活性的研究进展

Research progress on antitumor activity of Dendrobium alkaloids

近年来,我国对中医药重视程度逐渐提升,中医药研究引起人们广泛关注。石斛作为中医药学中的一种名贵药材,药用价值高,性味甘淡微咸,具有抗炎、养胃生津等功效。已有大量文献报道,石斛活性成分能够有效治疗肿瘤,并且其药效成分之一石斛生物碱对肿瘤细胞抑制作用效果较为显著。本文针对石斛生物碱成分抗肿瘤的作用进行分析,从石斛生物碱来源、药理活性及肿瘤细胞抑制机制展开综述,为石斛药用资源开发和利用提供参考。

In recent years,China's attention to traditional Chinese medicine has gradually increased,and the re-search of traditional Chinese medicine has attracted widespread attention.Dendrobium dendrobium,as a rare medicinal material in traditional Chinese medicine,has high medicinal value,which tastes sweet and slightly salty,and has anti-in-flammatory,stomach-nourishing,and fluid-producing effects.A large number of literatures have reported that the active components of Dendrobium can effectively treat tumors,and one of its effective components,Dendrobium alkaloids,has a significant inhibitory effect on tumor cells.In this paper,the anti-tumor effect of Dendrobium alkaloids was analyzed,and the sources,pharmacological activities,and anti-tumor mechanism of Dendrobium alkaloids were reviewed,in order to provide reference for the development and utilization of Dendrobium medicinal resources.