蚌埠地区无偿献血者TPPA阳性人群特征分析

Characteristics of TPPA positive voluntary blood donors in Bengbu

目的 分析蚌埠地区无偿献血者梅毒螺旋体颗粒凝集试验(TPPA)阳性人群特征,为招募低危献血者提供数据支持。方法 采用梅毒螺旋体颗粒凝集实验(TPPA)对蚌埠地区154 225例献血者标本中检出的250例TP-ELISA阳性标本进行确认检测,统计献血者信息,分析TPPA阳性献血者人群特征。结果 本研究共确认TPPA阳性标本107例,男性TPPA阳性率(0.71‰,56/79 047)与女性(0.68‰,51/75 178)比例接近1∶1,差异未见统计学意义(P>0.05)。35~44岁组TPPA阳性率(0.93‰,34/36 547)和45~60岁组(1.12‰,45/40 102)均显著高于18~34岁组(0.36‰,28/77 576),差异有统计学意义(P均<0.05)。初中及以下组TPPA阳性率(0.91‰,69/75 841)和高中及中职组阳性率(0.97‰,17/17 535)均显著高于大专及以上组(0.35‰,21/60 799),差异有统计学意义(P均<0.05)。首次献血组TPPA阳性率(1.48‰,86/58 259)显著高于重复献血组(0.22‰,21/95 966),差异有统计学意义(P均<0.05)。市区固定采血点TPPA阳性率(0.78‰,35/45 127)和县区固定采血点阳性率(0.81‰,27/33 368)均高于流动采血车(0.59‰,45/75730),差异未见统计学意义(P>0.05)。结论 蚌埠地区TPPA阳性的无偿献血者人群尚不存在明显的性别和区域分布的差异性,但是年龄在35岁以上,高中、中职及以下文化层度的首次献血人群,可能会存在较高的梅毒献血传播的风险。此外,固定采血点工作人员应继续提升重复献血者人群数量,从低危无偿献血者中采集安全的血液。

Objective To analyze the characteristics of Treponema pallidum particle agglutination(TPPA)positive voluntary blood donors in Bengbu area,and to provide data support for recruiting low-risk blood donors.Methods Treponema pallidum particle agglutination(TPPA)was used to confirm 250 TP-ELISA positive samples from 154225 blood donors in Bengbu area.The information of blood donors was analyzed,and the characteristics of TPPA positive blood donors were analyzed.Results A total of 107 TPPA positive specimens were confirmed in this study.The positive rate of TPPA in males(0.71%o,56/79047)and females(0.68%o,51/75178)was close to 1:1,there was no significant difference(P>0.05).The positive rates of TPPA in 35-44 years old group(0.93%o,34/36547)and 45-60 years old group(1.12%o,45/40102)were significantly higher than those in 18-34 years old group(0.36%o,28/77576),there were significant differences(P<0.05).The positive rate of TPPA in junior high school and below group(0.91%o,69/75841)and senior secondary and secondary vocational sections(0.97%o,17/17535)were significantly higher than those in junior college and above group(0.35%o,21/60799),there were significant differences(P<0.05).The positive rate of TPPA in the first time blood donation group(1.48%o,86/58259)was significantly higher than that in the repeated blood donation group(0.22%o,21/95966),there were significant differences(P<0.05).The positive rate of TPPA in urban fixed blood collection sites(0.78%o,35/45127)and county fixed blood collection sites(0.81%o,27/33368)was higher than that in mobile blood collection vehicles(0.59%o,45/75730),there was no significant difference(P>0.05).Conclusions There is no obvious difference in gender or regional distribution among TPPA-positive voluntary blood donors in Bengbu area,but the first time blood donors who are over 35 years old,senior secondary,secondary vocational sections and lower cultural levels may have a higher risk of syphilis blood donation transmission.In addition,the staff of fixed blood collection sites should continue to increase the number of repeated blood donors and collect safe blood from low-risk voluntary blood donors.