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胰十二指肠切除术后出血的治疗决策及预防措施 被引量:3

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摘要 胰十二指肠切除术后出血(post pancreaticoduodenectomy hemorrhage,PPH)是胰十二指肠切除术后最常见也是最严重的并发症之一,其发生率较高,发生时间不定,处理十分棘手,病死率较高,是胰腺外科医师的噩梦。PPH的发生严重影响患者预后生存,对其正确的认知和处理尤为重要,应秉承“预防为主、源头控制、早期发现、早期治疗”的原则。本文通过梳理PPH相关的循证医学依据,分析各类初始治疗方案的优劣性。对于早期PPH,应以手术治疗为主;对于迟发性PPH,应以介入治疗为主,手术的作用仍不能替代。对于前哨出血,应立刻采取干预措施。发生PPH行再手术止血时,手术方式应本着“胆胰分流”的目的和“损伤控制”的原则酌情处理。认识及制定正确的治疗决策能够显著提高干预PPH的成功率;同时,优化PPH的预防措施能有效降低PPH的发生率,这些对改善患者预后均具有重要而现实的意义。
出处 《中华普通外科杂志》 CSCD 北大核心 2023年第5期377-382,共6页 Chinese Journal of General Surgery
基金 国家自然科学基金(81871941,81827807,81872366)。
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