甲壳质酶蛋白40在脓毒症诊断中的运用价值

Application Value of the Enzyme Chitin 40 in the Diagnosis of Sepsis

脓毒症是各种感染引起宿主反应失调进而导致威胁生命的器官功能障碍。尽管医学技术在不断地进步,但其发病率和病死率仍居高不下,这使得脓毒症的早期诊断及干预治疗显得尤为重要。近年来,甲壳质酶蛋白40(YKL-40)作为一种新型的炎症标志物引起了广泛关注。研究发现,YKL-40参与了脓毒症的发生发展,在预测严重程度及预后具有重要临床意义。本文将对YKL-40的分子结构、作用机制及最新的研究进展做一综述。

Sepsis is a life-threatening organ dysfunction caused by various infections that cause host response disorders.Despite the continuous progress of medical technology,its incidence rate and mortality are still high,which makes the early diagnosis and intervention treatment of sepsis particularly important.In recent years,enzyme chitin 40(YKL-40) has attracted widespread attention as a novel inflammatory marker.Research has found that YKL-40 is involved in the occurrence and development of sepsis,and has important clinical significance in predicting severity and prognosis.In this article,we will review the molecular structure,mechanism of action and the latest research progress of YKL-40.