进展期胃癌腹腔镜手术近远期疗效观察

Short Term and Long Term Efficacy of Laparoscopic Surgery for Advanced Gastric Cancer

目的:探讨腹腔镜手术对进展期胃癌患者近远期疗效的影响。方法:选取2017年2月—2019年2月庆阳市人民医院收治的70例胃癌进展期患者,采取数字奇偶法均分为对照组与观察组,各35例。对照组采用传统开腹术,观察组采用腹腔镜手术,对比两组的手术结果。结果:观察组手术时间长于对照组,术中出血量少于对照组,切口长度短于对照组,近期康复情况、术后免疫功能优于对照组,纤维蛋白原及D-二聚体水平高于对照组,并发症发生率低于对照组,差异有统计学意义(P<0.05);两组淋巴结清扫数目及远期疗效比较,差异无统计学意义(P>0.05)。结论:采取腹腔镜手术治疗进展期胃癌,对患者机体创伤较小,免疫功能恢复情况较优,但会增加患者术后发生血液高凝状态风险,临床需结合患者机体情况选择合理手术方式,确保治疗效果。

Objective:To explore the impact of laparoscopic surgery on the short term and long term efficacy of patients with advanced gastric cancer.Method:A total of 70 patients with advanced gastric cancer admitted to Qingyang People's Hospital from February 2017 to February 2019 were selected and divided into a control group and an observation group using the digital parity method,with 35 patients in each group.The control group underwent traditional laparotomy,while the observation group underwent laparoscopic surgery.The surgical results of the two groups were compared.Result:The operation time of the observation group was longer than that of the control group,the intraoperative blood loss was less than that of the control group,and the incision length was shorter than that of the control group,recent recovery,and postoperative immune function of the observation group were better than those of the control group,the levels of fibrinogen and D-dimer were higher than those of the control group,and the incidence of complications was lower than that of the control group,the differences were statistically significant(P<0.05).There were no statistically significant differences in the number of lymph node dissection and long term efficacy between the two groups(P>0.05).Conclusion:Adopting laparoscopic surgery for the treatment of advanced gastric cancer has less trauma to the patient's body and better immune function recovery,but it increases the risk of developing hypercoagulable blood after surgery.Therefore,it is necessary to choose a reasonable surgical method based on the patient's physical condition in clinical practice to ensure treatment effectiveness.