摘要
Monitoring changes in the epidemiologic features between different severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)variants is key to understanding the evolution of viral fitness in the host population.Here,we analyzed a successfully contained local outbreak of the Delta variant that took place in Hunan,China,in July–August,2021.Detailed data on SARS-CoV-2 infections and their contacts were collected during the outbreak.By leveraging these data,we estimated key epidemiological parameters,including the incubation period,serial interval,and generation time.We constructed a generalized linear mixed-effects model(GLMM)to quantify risk factors for Delta infection and transmission.Between July 28 and August 15,2021,a total of 129 infections and their 2,118 close contacts were identified during the outbreak in Hunan Province.
基金
Supported by grants from the Key Program of the National Natural Science Foundation of China(82130093)
Shanghai Municipal Science and Technology Major Project(ZD2021CY001)
Hunan Provincial Innovative Construction Special Fund:Emergency response to COVID-19 outbreak(No.2020SK3012)
Chinese Academy of Medical Sciences Coronavirus Disease 2019 Science and Technology Research Project in 2020(No.2020HY320003)。
