摘要
海洋是世界上最大的生物资源宝库。由于海洋生态系统的特殊性(高压、高盐、低氧)给海洋生物之间的生存带来了非常激烈的竞争,导致很多海洋生物在其生命活动中产生了具有大量特殊结构和生物活性的次生代谢产物。本文总结了2016—2021年从海洋来源的微生物、动物、植物中提取的93个天然的抗真菌活性物质,并对它们的应用前景进行了展望。同时,还总结了这些海洋天然产物的抗真菌作用。
The ocean is the largest biological resource in the world.The special characteristics of marine ecological environment(high pressure,high salt,and low oxygen)make the competition for survival among marine organisms very fierce,resulting in many marine organisms producing a large number of secondary metabolites with special structures and biological activities during their life activities.In this paper,we summarized 93 natural antifungal active substances isolated from microorganisms,animals,and plants of marine sources from 2016 to 2021,and provided an outlook on their application prospects.In addition,the antifungal effects of marine natural products are reviewed.
作者
张颖
张诗
宁耀东
徐尧
卢小玲
马增岭
Zhang Ying;Zhang Shi;Ning Yao-dong;Xu Yao;Lu Xiao-ling;and Ma Zeng-ling(College of Life and Environmental Sciences,Wenzhou University,Wenzhou 325035;Department of Biochemistry and Molecular Biology,School of Basic Medical Sciences,Naval Medical University,Shanghai 200433)
出处
《中国抗生素杂志》
CAS
CSCD
北大核心
2023年第4期361-367,共7页
Chinese Journal of Antibiotics
基金
国家重点研发计划(No.2019YFC0312504)。
关键词
海洋微生物
次级代谢产物
抗真菌
Marine microorganism
Secondary metabolites
Antifungal activity
