美容缝合联合外用重组人表皮生长因子在腹壁竖切口愈合中的应用

Application of Cosmetic Suture Combined with Topical Recombinant Human Epidermal Growth Factor On Wound Healing of Vertical Abdominal Incision

目的:探讨腹壁竖切口美容缝合联合外用重组人表皮生长因子在妇科手术切口愈合中的作用。方法:选取2020年1月-2021年8月笔者医院收治的60例妇科需腹部手术患者为研究对象,随机分为对照组与观察组各30例。对照组患者腹部竖切口行美容缝合,观察组患者在此基础上联合外用重组人表皮生长因子,比较两组患者切口愈合效果、切口愈合时间、住院时间、切口瘢痕形成情况、切口瘢痕评分及术后切口并发症发生情况。结果:观察组总有效率为96.67%,高于对照组的60.00%(P<0.05);观察组患者切口愈合时间及住院时间均短于对照组(P<0.05);观察组患者瘢痕厚度、瘢痕宽度、瘢痕长度数值均小于对照组(P<0.05);观察组患者温哥华瘢痕评价量表(Vancouver scar evaluation scale,VSS)、患者瘢痕评价量表(Patient scar assessment scale,PSAS)、观测者瘢痕评价量表(Observer scar assessment scale,OSAS)评分均低于对照组(P<0.05);观察组患者术后切口并发症发生率3.33%,低于对照组的13.33%,但两组比较差异无统计学意义(P>0.05)。结论:妇科手术中采用竖切口美容缝合联合外用重组人表皮生长因子可有效促进患者手术切口愈合,减少切口并发症发生,减轻瘢痕形成程度,提高切口部位美观度,值得在临床上推广应用。

Objective To investigate the effect of cosmetic suture of vertical abdominal wall incision combined with topical recombinant human epidermal growth factor on incision healing in gynecological surgery.Methods A total of 60 gynecological patients who needed abdominal surgery admitted in the author`s hospital from January 2020 to August 2021 were selected as the research objects.They were randomly divided into a control group and an observation group,with 30 cases in each group.Patients in the control group were treated with vertical incision cosmetic suture,and patients in the observation group were treated with topical recombinant human epidermal growth factor on this basis.Incision healing effect,incision healing time and hospital stay,incision scar formation,incision scar score and postoperative incision complications were compared between the two groups.Results The total effective rate was 96.67%in the observation group,which was higher than 60.00%in the control group(P<0.05).The incision healing time and hospitalization time of the observation group were shorter than those of the control group(P<0.05).The values of scar thickness,scar width,and scar length in the observation group were lower than those in the control group(P<0.05).The Vancouver scar evaluation scale(VSS)and Patient scar assessment scale(PSAS)of patients in the observation group were compared,and observer scar assessment scale(OSAS)scores of the observation group were lower than those of the control group(P<0.05).The incidence of postoperative incision complications in the observation group was 3.33%,which was lower than 13.33%in the control group(P>0.05).Conclusion Vertical incision cosmetic suture combined with external application of recombinant human epidermal growth factor in gynecological surgery can effectively promote the healing of surgical incision,reduce the incidence of incision complications,reduce the degree of scar formation,and improve the appearance of incision site.This method is worthy of clinical application.