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宫颈液基细胞学检查结果与宫颈癌前病变高危型HPV感染的关系分析 被引量:2

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摘要 目的探究宫颈液基细胞学检查(TCT)结果与宫颈癌前病变高危型HPV(HR-HPV)感染的关系。方法选取2019年6月—2021年6月肇庆市中医院收治的已确诊为宫颈癌前病变的78例患者作为研究对象,均行HR-HPV检查和TCT检查。分析患者的HR-HPV阳性检出率及具体分型,并根据其是否感染高危型HPV分为感染组和非感染组。收集患者的基线资料及TCT检查结果,采用Logistic多因素回归模型分析TCT检查结果与宫颈癌前病变HR-HPV感染的关系。结果78例宫颈癌前病变患者中,HR-HPV感染的阳性率为58.97%,其中HPV16,18,31,38,58型及其他型的阳性率分别为24.36%,15.38%,7.69%,3.85%,5.13%及2.56%。单因素分析结果显示,TCT检查结果细胞学病变程度、生育史、阴道炎症史、性伴侣个数、阴道不规则出血是宫颈癌前病变患者HR-HPV感染的影响因素(P<0.05)。Logistic回归分析结果显示,TCT检查结果细胞学病变程度高、有阴道炎症史、性伴侣个数多是宫颈癌前病变患者HR-HPV感染的独立危险因素(P<0.05)。结论宫颈癌前病变患者高危型HPV感染率较高,以HPV16,18感染为主,其中TCT检查结果细胞学病变程度越高,患者感染HR-HPV的概率越大。
机构地区 肇庆市中医院
出处 《基层医学论坛》 2023年第17期63-65,共3页 The Medical Forum
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