微量元素与儿童免疫功能的认识及进展

Understanding and Progress of Trace Elements and Immune Function in Children

随着社会的发展及人们生活方式的改变,蛋白质-能量营养不良已显著减少,但微量元素缺乏或不平衡的问题却日益凸显。微量元素与人体健康密切相关,尤其是儿童,其常以辅酶的形式参与机体各种代谢,促进人体生长发育、维护中枢神经系统完整性、参与机体免疫应答等。微量元素是维护人体免疫功能的重要因素,对机体免疫功能的影响是多方面的,特别是对淋巴组织、细胞免疫功能和吞噬细胞杀菌作用的影响更明显。因此,阐明微量元素对机体免疫功能的作用机制,对保障儿童的健康、预防相关疾病的发展具有重要意义。本文主要通过对铁、铜、硒免疫机制的探讨初步阐述微量元素与儿童免疫功能的关系。

With the development of society and the change of people's lifestyle,protein-energy malnutrition has been significantly reduced,but the lack or imbalance of trace elements has become increasingly prominent.Trace elements are closely related to human health.they are often involved in various metabolism in the form of coenzymes,which promote human growth and development,maintain the integrity of the central nervous system,participate in the immune response of the body and so on.Studies have shown that trace elements are an important factor in maintaining human immune function,and its effects on immune function are various,especially on lymphoid tissue,cellular immune function and bactericidal effect of phagocytes.Therefore,it is of great significance to clarify the mechanism of trace elements on the immune function of the body in order to ensure the health of children and prevent the development of related diseases.In this paper,the relationship between trace elements and immune function of children was preliminarily expounded by discussing the immune mechanism of iron,copper and selenium.