采用证候分层诊断法分析原发性肺癌患者证候分布规律

Syndromes Distribution of Patients with Primary Lung Cancer Based on Syndrome Stratification Diagnosis

目的:采用证候分层诊断法分析原发性肺癌患者证候分布规律。方法:收集2020年6月1日至2022年5月31日在中国中医科学院广安门医院肿瘤科门诊就诊及住院的514例肺癌患者资料,采用证候分层辨证后分析其证候分布规律。结果:原发性肺癌患者证候分布的一级诊断实证多于虚证;二级诊断以气逆证、血瘀证、痰证、饮证、实热证、气虚证最多见;配属病位后,三级诊断以肺气逆证、肺血瘀证、肺痰证、脑血瘀证、肺气虚证为多见。肺癌患者病位涉及广泛,以肺、脾、胃、脑、肝为主。肺癌患者的证候分布与病理类型、治疗手段显著相关,不同分期患者的证候分布总体上差异不明显,但个别证型仍与特定分期相关。结论:原发性肺癌患者证候表现虚实夹杂,病性与病位均涉及较广,提示肺癌病机复杂,病情多变,病理类型、疾病分期、治疗手段均是影响肺癌证候分布的相关因素。

Objective:To analyze the syndrome distribution of patients with primary lung cancer by syndrome stratification diagnosis.Methods:The data of 514 patients with lung cancer who were treated and hospitalized in the Department of Oncology,Guang′anmen Hospital,Chinese Academy of traditional Chinese Medicine from June 1,2020 to May 31,2022 were collected.Results:In the primary diagnosis,the syndrome distribution of patients with primary lung cancer was more positive than deficiency syndrome;in the secondary diagnosis,Qi inversion syndrome,blood stasis syndrome,Phlegm syndrome,Drink syndrome,excess Heat syndrome and Qi deficiency syndrome were the most common.Lung Qi reverse syndrome,lung blood stasis syndrome,lung phlegm syndrome,brain blood stasis syndrome and Lung Qi deficiency syndrome are the most common in the third stage diagnosis.Patients with lung cancer are involved in a wide range of diseases,mainly lung,spleen,stomach,brain and liver.The syndrome distribution of patients with lung cancer is significantly related to pathological types and treatment methods.There is no significant difference in syndrome distribution among patients with different stages,but individual syndrome types are still related to specific stages.Conclusion:The syndromes of patients with primary lung cancer are mixed with deficiency and excess,and the disease and location are involved widely,suggesting that the pathogenesis of lung cancer is complex and changeable,and pathological types,disease stages and treatment methods are all related factors affecting the distribution of lung cancer syndromes.