臭氧灌洗+玻璃酸钠关节腔注射治疗老年退行性膝关节痛的效果及对膝关节功能、活动能力的影响

Effect of ozone lavage + sodium hyaluronate intra-articular injection in the treatment of senile degenerative knee joint pain and its influences on knee joint function and activity ability

目的 探讨臭氧灌洗+玻璃酸钠关节腔注射治疗老年退行性膝关节痛的效果及对膝关节功能、活动能力的影响。方法 选取2019年5月至2021年5月本院收治的96例老年退行性膝关节痛患者为研究对象,依据入院编号的奇偶性将其分为对照组与观察组,各48例。对照组使用氯化钠溶液灌洗+玻璃酸钠关节腔注射治疗,观察组使用臭氧灌洗+玻璃酸钠关节腔注射治疗。比较两组的临床疗效、膝关节功能、韧带损伤及缺损情况、生活自理能力、下肢运动功能、活动疼痛感及不良反应发生情况。结果 观察组的治疗总有效率为95.83%,显著高于对照组的70.83%,差异具有统计学意义(P<0.05)。治疗后,两组的Lysholm、Barthel、Fugl-Meyer评分均高于治疗前,国际膝关节文献委员会(IKDC)评分低于治疗前,差异具有统计学意义(P<0.05);治疗后,观察组的Lysholm、Barthel、Fugl-Meyer评分高于对照组,IKDC评分低于对照组,差异具有统计学意义(P<0.05)。治疗1、4、8、16周,两组的活动疼痛感均低于治疗前,差异具有统计学意义(P<0.05);治疗1、4、8、16周,观察组的活动疼痛感均低于对照组,差异具有统计学意义(P<0.05)。两组的不良反应总发生率比较,差异无统计学意义(P>0.05)。结论 臭氧灌洗+玻璃酸钠关节腔注射治疗老年退行性膝关节痛的效果较好,可改善患者的膝关节功能及活动能力,降低其活动疼痛感,具有较高的临床应用价值。

Objective To investigate the effect of ozone lavage+sodium hyaluronate intra-articular injection in the treatment of senile degenerative knee joint pain and its influences on knee joint function and activity ability.Methods A total of 96 patients with senile degenerative knee joint pain admitted in our hospital from May 2019 to May 2021 were selected as the research objects.According to the parity of admission number,the patients were divided into control group and observation group,with 48 cases in each group.The control group was treated with sodium chloride lavage+sodium hyaluronate intra-articular injection,and the observation group was treated with ozone lavage+sodium hyaluronate intra-articular injection.The clinical treatment effect,knee joint function,ligament injury and defect situation,self-care ability,lower limb motor function,activity pain and adverse reactions were compared between the two groups.Results The total effective rate of treatment in the observation group was 95.83%,which was significantly higher than 70.83%in the control group,and the difference was statistically significant(P<0.05).After treatment,the Lysholm,Barthel and Fugl-Meyer scores of the two groups were higher than those before treatment,the International Knee Documentation Committee(IKDC)score was lower than that before treatment,and the differences were statistically significant(P<0.05);after treatment,the Lysholm,Barthel and Fugl-Meyer scores of the observation group were higher than those of the control group,the IKDC score was lower than that of the control group,and the differences were statistically significant(P<0.05).At 1,4,8 and 16 weeks of treatment,the activity pain of the two groups was lower than that before treatment,and the difference was statistically significant(P<0.05);at 1,4,8 and 16 weeks of treatment,the activity pain of the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion The ozone lavage+sodium hyaluronate intra-articular injection in the treatment of senile degenerative knee joint pain has better effect,it can improve the knee joint function and activity ability of patients,and reduce their activity pain,which has higher clinical application value.