恩格列净联合胰岛素强化治疗对老年2型糖尿病患者血糖控制、抗氧化能力及胰岛素用量的影响分析

Analysis of the Effects of Empagliflozin Combined with Insulin Intensive Treatment on Blood Glucose Control,Antioxidant Capacity and Insulin Dosage in Elderly Patients with Type 2 Diabetes Mellitus

目的研究分析老年2型糖尿病患者采用恩格列净联合胰岛素强化治疗对其血糖控制、抗氧化能力及胰岛素用量等方面的影响。方法选取在2020年12月—2021年11月于荣成市中医院就诊的110例2型糖尿病老年患者为研究对象,采用抽签的方式将患者分为两组,每组55例。常规组采用胰岛素强化治疗,观察组采用恩格列净+胰岛素强化治疗,比较两组疗效。结果治疗后,观察组血糖较治疗前可见大幅度下降,且明显低于常规组,差异有统计学意义(P<0.05)。观察组抗氧化能力优于常规组,胰岛素用量略低于常规组,差异有统计学意义(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论2型糖尿病老年患者采取恩格列净+胰岛素强化治疗,用药后能够充分调控患者机体血糖水平,干预患者机体状态,可见良好功效。

Objective To study and analyze the effects of empagliflozin combined with insulin intensive treatment on blood glucose control,antioxidant capacity and insulin dosage in elderly patients with type 2 diabetes mellitus.Methods A total of 110 elderly patients with type 2 diabetes who received treatment in Rongcheng Hospital of Traditional Chinese Medicine from December 2020 to November 2021 were selected as the study objects,and the patients were divided into two groups by drawing lots,with 55 patients in each group.The conventional group was treated with intensive insulin therapy,and the observation group was treated with Engliazine+insulin intensive therapy.The curative efficacy of the two groups was compared.Results After treatment,the blood glucose in the observation group was was significantly decreased compared with that before treatment,and was significantly lower than that in the conventional group,the difference was statistically significant(P<0.05).The antioxidant capacity of the observation group was better than that of the conventional group,and the insulin dosage was slightly lower than that of the conventional group,the difference was statistically significant(P<0.05).There was no statistical significance difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Type 2 diabetes mellitus elderly patients take empagliflozin+insulin intensive treatment,after the use of the drug can fully regulate the blood glucose level of the patient′s body,intervention in the state of the patient′s body,with good efficacy.