摘要
The coverage and quality of screening are essential for reducing the incidence of cervical precancers and cervical cancer.This multicenter study aimed to investigate the relationship between screening quality and the detection of cervical precancers and cervical cancer.The study was conducted from June to December 2021 in six hospitals across six provinces.The 2,945 participants were non-pregnant women who underwent colposcopy examinations.The average age of participants was 40.9±11.5 years old.Only 6.9%of participants had received human papillomavirus(HPV)vaccination.A total of 92.6%of participants had abnormal cervical screening results.Of the participants,577 had high-grade squamous intraepithelial lesions(HSIL)or worse(≥HSIL),with a detection rate of 19.6%.Univariate analysis indicated that a lack of cervical cancer screening history in the past five years,as well as positive cervical screening and abnormal colposcopic impression,were independent associated factors of the≥HSIL detection rate.A multivariable logistic regression showed that positive cervical screening[odds ratio(OR)=1.75,95%confidence interval(CI):1.07–2.86]was a risk factor for detecting≥HSIL.Low-grade,high-grade,and cancer of colposcopic impression were associated with a higher risk for detecting≥HSIL(OR=2.94,95%CI:2.13–4.08;OR=36.64,95%CI:26.07–51.48).It is important to disseminate health knowledge to improve public awareness of cervical cancer prevention and to enhance the capacity building of professional staff to improve the quality of cervical cancer screening.
