The Associated Factors of SARS-CoV-2 Reinfection by Omicron Variant—Guangdong Province,China,December 2022 to January 2023

Summary What is already known about this topic?Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)reinfection by variants is being reported commonly and has caused waves of epidemic in many countries.Because of dynamic zero policy,the SARSCoV-2 reinfection was less reported in China.What is added by this report?SARS-CoV-2 reinfections were observed in Guangdong Province between December 2022 and January 2023.This study estimated that the reinfection incidence was 50.0%for the original strain primary infections,35.2%for the Alpha or Delta variants,and 18.4%for the Omicron variant;The reinfection incidence within 3-6 months after primary infection by Omicron variant was 4.0%.Besides,96.2%reinfection cases were symptomatic while only 7.7%sought medical attention.What are the implications for public health practice?These findings suggest a reduced likelihood of an Omicron-driven epidemic resurgence in the short term but emphasize the importance of maintaining vigilant surveillance of emerging SARS-CoV-2 variants and conducting population-based antibody level surveys to inform response preparedness.