置管溶栓联合髂静脉腔内治疗髂静脉压迫综合征伴下肢深静脉血栓形成的临床效果观察

Clinical observation of intravenous thrombolysis combined with iliac vena cava in treatment of iliac vein compression syndrome with deep venous thrombosis of lower extremities

目的 观察置管溶栓联合髂静脉腔内治疗髂静脉压迫综合征伴下肢深静脉血栓形成的临床效果。方法 从阜外华中心血管病医院2022年1月—2023年1月收入院治疗的髂静脉压迫综合征伴下肢深静脉血栓患者中选取106例作为此次研究对象,以随机数字表法分组为对照组和观察组,对照组(n=53)采取置管溶栓进行治疗,观察组(n=53)采取置管溶栓联合髂静脉腔内进行治疗,观察对比两组患者血栓的清除情况、健患肢的周径差、患肢的消肿率。结果 治疗后,观察组血栓的清除率(93.67±5.13)%,优于对照组的(81.93±5.29)%,组间差异有统计学意义(P<0.05)。治疗后,观察组健患肢的周径差低于对照组,患肢的消肿率优于对照组,组间差异有统计学意义(P<0.05)。结论 在髂静脉压迫综合征伴下肢深静脉血栓形成患者中应用置管溶栓联合髂静脉腔内治疗,可有效改善血栓的清除情况,降低患者健患肢的周径差,提高患肢的消肿率。

Objective To observe the clinical effect of intravenous thrombolysis combined with iliac vena cava in the treatment of iliac vein compression syndrome with deep venous thrombosis of lower extremities.Methods Totally 106 cases of iliac vein compression syndrome with deep venous thrombosis of lower extremity received treatment in our hospital from Jan.2022 to Jan.2023 were selected as the study objects,and were divided into control group and observation group by numerical random table method.The control group(n=53)received catheterization thrombolytic therapy.Observation group(n=53)was treated with intravenous thrombolysis combined with iliac vena cava,and the thrombus clearance,circumference difference of healthy limb and swelling reduction rate of affected limb were observed and compared between the two groups.Results After treatment,the thrombus clearance rate in the observation group was(93.67±5.13)%,which was better than that in the control group(81.93±5.29)%,and the difference between groups was statistically significant(P<0.05).After treatment,the circumference difference of healthy limbs in the observation group was lower than that in the control group,and the detumescence rate of affected limbs in the observation group was better than that in the control group,and the difference between groups was statistically significant(P<0.05).Conclusion In patients with iliac vein compression syndrome with deep venous thrombosis of lower extremity,intravenous thrombolysis combined with iliac vein intraventricular therapy can effectively improve the clearance of thrombus,reduce the circumference difference of healthy limb,and improve the detumescence rate of affected limb.