摘要
Dear Editor,Previous studies have proved that regulatory T cell(Treg)insufficiency contributed to the development of autoimmune conditions including systemic lupus erythematosus(SLE).Conventional immunosuppressive treatment was reported to downregulate beneficial Tregs together with pathogenic effector immune cells,which may impede a rapid achievement of optimal therapeutic effects.
基金
supported by the Natural Science Foundation of China (81971520,32141004,82171775)
Project (RDGS2022-05) supported by Peking University People's Hospital Scientific Research Development Funds
Beijing Children's Hospital Young Investigator Program.