A thermodynamic model showing that information recording can drive active ion transport

Dear Editor,Ion gradients are characteristic features of a living cell that do not represent thermodynamic equilibrium.These unequilibrium status are maintained by various ion pumps such as Na-K-ATPase,which are known as the P-type ATPases.Working mechanism of Na-K-ATPase is described as Post-Albers cycle1(Fig.1a).However,the reaction scheme is non-Michaelis-Menten kinetics assembled from transient-state results,which can hardly be used to rebuild the real reaction cycle.