伦理视角下孕妇参与临床研究的思考

Reflection on the Current Situation of Pregnant Women's Participation in Clinical Research from an Ethical Perspective

由于孕妇生理的特殊性,一般的临床研究都将孕妇排除在外。因此,目前全球都缺乏患病孕妇精准用药的证据,缺乏证据使患病孕妇在怀孕期间使用药物面临极大风险。是否纳入孕妇作为临床研究受试者一直是伦理讨论的焦点,通过从伦理视角对孕妇参与临床研究进行广泛概述,探讨孕妇参与临床研究面临的风险与挑战,为如何公平有效地纳入孕妇受试者,推进孕妇临床研究提供理论依据和思考路径。

Due to the physiological peculiarities of pregnant women,general clinical studies exclude pregnant women.Therefore,there is a lack of evidence of precise medication for pregnant women with diseases worldwide,which poses a significant risk for them to use medication during pregnancy.Whether to include pregnant women as subjects in clinical research has always been a focus of ethical discussion.By providing a broad overview of pregnant women's participation in clinical research from an ethical perspective,this paper explored the risks and challenges faced by pregnant women's participation in clinical research,and provided theoretical basis and thinking paths for how to fairly and effectively include pregnant women as subjects and promoting clinical research on pregnant women.