摘要
肝内胆管癌(intrahepatic cholangiocarcinoma, ICC)是发病率仅次于肝细胞癌的肝脏恶性肿瘤,根治性外科切除是其获得治愈的唯一方法。由于ICC兼具肝脏和胆道恶性肿瘤的生物学特点,如何规范根治性切除手术、切缘多少、解剖性肝切除的临床意义、联合血管切除是否获益、淋巴结清扫与预后相关性、淋巴结清扫的意义与术前决策、微创手术是否保障手术的安全性与有效性、综合治疗在围手术期应用的意义等相关问题仍存在不少争议。此文就ICC外科治疗的以上热点问题进行了探讨。
Intrahepatic cholangiocarcinoma(ICC)is a malignant liver tumor with an incidence secondary only to hepatocellular carcinoma(HCC).Radical surgical resection remains a sole curative option.It has the biological characteristics of both liver and biliary tract malignant tumors.There are still many outstanding controversies on number of resection margins,clinical significance of anatomical hepatectomy,whether or not combined vascular resection beneficial,correlation between lymph node dissection and prognosis,significance of lymph node dissection and preoperative decision-making,whether mini-invasive procedure ensured the safety and effectiveness of surgery and significance of comprehensive treatment during perioperative period.This review summarized several hot issues in surgery for ICC.
作者
陈家璐
于小鹏
唐玥
覃德龙
汤朝晖
全志伟
Chen Jialu;Yu Xiaopeng;Tang Yue;Qin Delong;Tang Zhaohui;Quan Zhiwei(Department of General Surgery,Xinhua Hospital Affiliated to Shanghai,Jiao Tong University School of Medicine,Shanghai 200092,China)
出处
《腹部外科》
2023年第3期160-164,183,共6页
Journal of Abdominal Surgery
基金
国家自然科学基金(81772521)
上海交通大学医学院附属新华医院院级临床研究培育基金(17CSK06)
上海交通大学医学院多中心临床研究(DLY201807)。
关键词
肝内胆管癌
外科治疗
根治性切除
淋巴结清扫
围手术期综合治疗
Intrahepatic cholangiocarcinoma
Surgical management
Radical resection
Lymph node dissection
Comprehensive treatment during perioperative period
