肝内胆管癌的诊疗进展

Advances in diagnosis and treatment of intrahepatic cholangiocarcinoma

胆管癌是起源于肝内或者肝外胆管的恶性肿瘤,根据其解剖学的不同,主要分为肝内胆管癌和肝外胆管癌。肝内胆管癌的发病率在过去十几年中一直呈现上升的趋势。由于肝内胆管癌的隐蔽性,多数被确诊的病人已失去了手术机会,且高度侵袭性使得切除率与治愈率仍然较低,对于可手术切除病人,外科手术切除仍然是主要治疗方法,不可手术的病人通常以辅助放化疗、肝移植、局部治疗作为主要治疗手段。

Cholangiocarcinoma is a malignant tumor originating from intrahepatic or extrahepatic bile duct.According to its anatomy,it is divided largely into intrahepatic cholangiocarcinoma(ICC)and extrahepatic cholangiocarcinoma(ECC).The incidence of ICC has been rising over the last decade.Because of concealing nature of ICC,most diagnosed patients have wasted the opportunity of operation and its high invasiveness renders resection and cure rates quite low.For resectable cases,surgical resection is perferred.Unoperable individuals respond well to adjuvant radiochemotherapy,liver transplantation and local therapy.