HR-CT鉴别结节性甲状腺肿与微小甲状腺乳头状瘤的价值

Value of HR-CT in the Differential Diagnosis of Nodular Goiter and Papillary Thyroid Microcarcinoma

目的探讨高分辨计算机断层扫描(HR-CT)鉴别结节性甲状腺肿(NG)与微小甲状腺乳头状瘤(PTMC)的价值。方法回顾性选取2019年5月-2022年6月收治的76例NG患者(NG组)和82例PTMC患者(PTMC组)作为研究对象,两组均行HR-CT,分析HR-CT在鉴别结节性甲状腺肿与微小甲状腺乳头状瘤的价值。结果HR-CT对NG和PTMC诊断的符合率为分别为97.37%,90.24%,两组符合率比较差异无统计学意义(P>0.05);NG组和PTMC组在瘤体形态、结节数、增强后边界情况、细颗粒状钙化、边缘中断症、假包膜方面差异具有统计学意义(P<0.05);多因素回归显示,瘤体形态、增强后边界、边缘中断症、假包膜均为NG和PTMC的独立影响因素(P<0.05)。结论HR-CT在NG与PTMC的鉴别诊断方面具有重要价值,临床可根据瘤体形态、增强后边界、边缘中断症、假包膜辅助鉴别诊断。

Objective To explore the value of high-resolution computed tomography(HR-CT)in the differential diagnosis of nodular goiter(NG)and papillary thyroid microcarcinoma(PTMC).Methods A total of 76 patients with NG(NG group)and 82 patients with PTMC(PTMC group)were retrospectively enrolled as the research objects between May 2019 and June 2022.All underwent HR-CT.The value of HR-CT in the differential diagnosis of NG and PTMC was analyzed.Results The coincidence rates of HR-CT in the diagnosis of NG and PTMC were 97.37%and 90.24%,and the difference was not statistically significant(P>0.05).The differences in tumor morphology,number of nodules,borders after enhancement,fine granular calcification,edge disruption and pseudocapsule between the two groups were statistically significant(P<0.05).Multivariate regression analysis showed that tumor morphology,borders after enhancement,edge disruption and pseudocapsule were independent influencing factors of NG and PTMC(P<0.05).Conclusion HR-CT is of great value in the differential diagnosis of NG and PTMC.Clinically,tumor morphology,borders after enhancement,edge disruption and pseudocapsule can be applied in the differential diagnosis.