敌草快中毒性脑病一例报道及影像学分析

Diquat Toxic Encephalopathy:A Case Report and Imaging Analysis

敌草快是一种非选择性速效灭生性除草剂,与百草枯同属联吡啶类化合物。据报道,美国敌草快中毒以职业相关因素为主(8%~44%),且病死率低(<1%~3%)。我国是于近年来禁止百草枯后,敌草快才在市场中普及,因此对敌草快中毒的认识不足,病死率显著高于发达国家。敌草快主要损害靶器官为肝和肾,对中枢神经系统也有累及。本文主要报道一例年轻女性误服敌草快致严重的中枢神经系统损伤的案例,该患者存在典型的敌草快中毒性脑损伤临床及影像学表现,具有一定指导意义。

Diquat is a non selective,fast acting,inactivating herbicide that is in the same bipyridyl class as paraquat.It has been reported that diquat poisoning in the United States is dominated by occupation related factors(8%~44%),and the mortality is low(<1%~3%).Our country is only popular in the market after the prohibition of paraquat in recent years,so the understanding of diquat poisoning is insufficient and the mortality is significantly higher than that of developed countries.Diquat mainly damages target organs as liver and kidney,and also has central nervous system involvement.In this paper,we mainly reported a case of severe CNS injury caused by mistaking diquat to a young female,who had typical clinical and imaging findings of toxic brain injury caused by diquat,which was instructive.